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Thus, ferroptosis induction in HSCs by targeting the system Xc-/GPX4 axis might be an effective approach to ameliorate liver fibrosis
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The twice-daily preparation has historically shown higher nausea rates of up to 30-40% of patients, while the extended-release formulation demonstrates improved tolerability
Lactylation, a post-translational modification (PTM) identified in 2019, introduces a novel mechanism by which lactate can modulate protein function and gene expression [3]
A subgroup of patients in the study had pre-existing diabetic retinopathy
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